How and where to order Hydralazine (Apresoline) 25 mg tablets online:
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| Sellers: | HYDRALAZINE STORES
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| Prices: | from $0.56 per pill
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| Forms: | 25 mg tablets
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| Quantity: | 30, 60, 90, 180 pills
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| Type: | Apresol brand, Hylazine brand, Apresoline generic
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| Payment: | Visa, Mastercard, AmEx, Cryptocurrencies
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| Delivery: | Regular and express mail service
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| Shipping: | Worldwide, including USA, UK, Europe, Canada, Australia |
Indications and usage:
Apresoline (Hydralazine) tablets are indicated for:
essential hypertension, malignant hypertension, alone or as an adjunct
high blood pressure in pregnancy
hypertensive emergency
very high blood pressure resulting in symptoms
heart failure
myelodysplastic syndrome
Contraindications:
Hypersensitivity to hydralazine or other inactive components of these tablets.
Coronary artery disease.
Mitral valvular rheumatic heart disease.
Dosage forms and strengths:
Hydralazine (Apresoline) 10 mg, 25 mg, 50 mg, 100 mg tablets.
Dosage and administration:
Initiate therapy with hydralazine in gradually increasing dosages; adjust according to individual response. Start with 10 mg four times daily for the first 2 to 4 days, increase to 25 mg four times daily for the balance of the first week. For the second and subsequent weeks, increase dosage to 50 mg four times daily. For maintenance, adjust dosage to the lowest effective levels.
The incidence of toxic reactions, particularly the L.E. cell syndrome, is high in the group of patients receiving large doses of this medication.
In a few resistant patients, up to 300 mg daily may be required for a significant antihypertensive effect. In such cases, a lower dosage of hydralazine combined with a thiazide and/or reserpine or a beta blocker may be considered. However, when combining therapy, individual titration is essential to ensure the lowest possible therapeutic dose of each drug.
Warnings:
In a few patients this medicine may produce a clinical picture simulating systemic lupus erythematosus including glomerulonephritis. In such patients Apresoline (Hydralazine) should be discontinued unless the benefit-to-risk determination requires continued antihypertensive therapy with this drug. Symptoms and signs usually regress when the drug is discontinued but residua have been detected many years later. Long-term treatment with steroids may be necessary.
Precautions:
Myocardial stimulation produced by this drug can cause anginal attacks and ECG changes of myocardial ischemia.
The "hyperdynamic" circulation caused by Apresoline may accentuate specific cardiovascular inadequacies.
In hypertensive patients with normal kidneys who are treated with hydralazine pills, there is evidence of increased renal blood flow and a maintenance of glomerular filtration rate.
Peripheral neuritis, evidenced by paresthesia, numbness, and tingling, has been observed.
The Apresoline tablets 100 mg contain tartrazine, which may cause allergic-type reactions (including bronchial asthma) in certain susceptible individuals.
Overdosage:
Signs and symptoms:
Signs and symptoms of overdosage by hydralazine include hypotension, tachycardia, headache, and generalized skin flushing. Complications can include myocardial ischemia and subsequent myocardial infarction, cardiac arrhythmia, and profound shock.
Treatment:
There is no specific antidote.
The gastric contents should be evacuated, taking adequate precautions against aspiration and for protection of the airway. An activated charcoal slurry may be instilled if conditions permit. These manipulations may have to be omitted or carried out after cardiovascular status has been stabilized, since they might precipitate cardiac arrhythmias or increase the depth of shock.
Support of the cardiovascular system is of primary importance. Shock should be treated with plasma expanders. If possible, vasopressors should not be given, but if a vasopressor is required, care should be taken not to precipitate or aggravate cardiac arrhythmia.
Tachycardia responds to beta blockers. Digitalization may be necessary, and renal function should be monitored and supported as required.
No experience has been reported with extracorporeal or peritoneal dialysis.
Side effects, adverse reactions:
Most common adverse reactions of this medicine are headache, anorexia, diarrhea, vomiting, nausea, palpitations, tachycardia, angina pectoris.
To report suspected side effects of Apresoline (Hydralazine) tablets contact Novartis pharmaceutical company, or to your local FDA.
Drug interactions:
Monoamine oxidase inhibitors inhibitors should be used with caution in patients receiving this hydralazine tablets.
Medicines used to treat high blood pressure or heart conditions such as beta-blockers (e.g. propranolol, metoprolol); ACE inhibitors and calcium channel blockers.
When other potent parenteral antihypertensive drugs, such as diazoxide, are used in combination with this medication, patients should be continuously observed for several hours for any excessive fall in blood pressure. Profound hypotensive episodes may occur when diazoxide injection and hydralazine are used concomitantly.
Diuretics, also called fluid or water pills.
Tricyclic antidepressants, and other medications to treat depression.
Medications used to treat certain mental and emotional conditions such as schizophrenia.
Adrenaline, a drug used in emergency situations or to treat a severe allergic reaction.
Drug/food interactions:
Administration of Hydralazine (Apresoline) tablets with food results in higher plasma levels.
Usage in specific populations:
Pregnancy
There are no adequate and well-controlled studies of hydralazine in pregnant women. Although clinical experience does not include any positive evidence of adverse effects on the human fetus, hydralazine should be used during pregnancy only if the expected benefit justifies the potential risk to the fetus.
Nursing mothers
This medicine has been shown to be excreted in breast milk.
Pediatric use
Safety and effectiveness in pediatric patients have not been established in controlled clinical trials, although there is experience with the use of this drug in these patients.
Information for patients:
Patients should be informed of possible side effects and advised to take the medication regularly and continuously as directed.
Tell your healthcare provider if you are taking any other medications, including any that you get without a prescription from your pharmacy, supermarket or health food shop.
Tell your doctor if you plan to have surgery.
If you become pregnant while taking hydralazine, tell your doctor immediately.
Tell your health professional as soon as possible if you do not feel well while you are taking these tablets.
Tell your physician or pharmacist if you notice anything that is making you feel unwell.
Where to buy hydralazine online:
To purchase Apresoline (Hydralazine) 25 mg tablets from reliable online pharmacies and drugstores at low prices please use resources described above on this webpage.
Here is a list of popular medications containing hydralazine hydrochloride as a main active pharmaceutical ingredient; their trade names, forms, doses, companies - manufacturers, distributors, suppliers, researchers and developers:
| Trade name of the drug |
Pharmaceutical forms and doses |
Companies |
| Alphapress |
Tablets; Oral; 25 mg, 50 mg |
AlphapharmViatris |
| Apo-Hydralazine |
Tablets; Oral; 10 mg, 25 mg, 50 mg |
Apotex |
| Apresol |
Tablets; Oral; 25 mg, 50 mg |
Ordain Health Care |
| Apresoline |
Injectable; Injection; 20 mg / mlTablets; Oral; 10 mg, 25 mg, 50 mg, 100 mg |
NovartisAmdipharmSteriMax |
| Hydrapres |
Injectable; Injection; 20 mg / mlTablets; Oral; 25 mg, 50 mg |
Rubio Laboratorios |
